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Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells
An epigenetic component, especially aberrant DNA methylation pattern, has been shown to be frequently involved in sporadic breast cancer development. A growing body of literature demonstrates that combination of agents, i.e. nucleoside analogues with dietary phytochemicals, may provide enhanced ther...
Autores principales: | Lubecka, Katarzyna, Kaufman-Szymczyk, Agnieszka, Cebula-Obrzut, Barbara, Smolewski, Piotr, Szemraj, Janusz, Fabianowska-Majewska, Krystyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321577/ https://www.ncbi.nlm.nih.gov/pubmed/30544666 http://dx.doi.org/10.3390/ijms19123970 |
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