Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives

A series of novel 1,3,4-triarylpyrazoles containing different heterocycles has been prepared, characterized and screened for their in vitro antiproliferative activity against HePG-2, MCF-7, PC-3, A-549 and HCT-116 cancer cell lines. The biological results revealed that compound 6 showed the highest...

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Detalles Bibliográficos
Autores principales: Nossier, Eman S., Abd El-Karim, Somaia S., Khalifa, Nagy M., El-Sayed, Ali S., Hassan, Emad S. I., El-Hallouty, Salwa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321587/
https://www.ncbi.nlm.nih.gov/pubmed/30477238
http://dx.doi.org/10.3390/molecules23123074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321587/
https://www.ncbi.nlm.nih.gov/pubmed/30477238
http://dx.doi.org/10.3390/molecules23123074

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