Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)-N-1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression

Osteoclasts are large multinucleated cells which are induced by the regulation of the receptor activator of nuclear factor kappa-Β ligand (RANKL), which is important in bone resorption. Excessive osteoclast differentiation can cause pathologic bone loss and destruction. Numerous studies have targete...

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Detalles Bibliográficos
Autores principales: Ahn, Sun-Hee, Chen, Zhihao, Lee, Jinkyung, Lee, Seok-Woo, Min, Sang Hyun, Kim, Nam Doo, Lee, Tae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321589/
https://www.ncbi.nlm.nih.gov/pubmed/30501117
http://dx.doi.org/10.3390/molecules23123139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321589/
https://www.ncbi.nlm.nih.gov/pubmed/30501117
http://dx.doi.org/10.3390/molecules23123139

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