Quantum Mechanical/Molecular Mechanical Analysis of the Catalytic Mechanism of Phosphoserine Phosphatase

Phosphoserine phosphatase (PSP), a member of the haloacid dehalogenase (HAD) superfamily that comprises the vast majority of phosphotransferases, is likely a steady-state regulator of the level of d-serine in the brain. The proposed catalytic cycle of PSP consists of a two-step mechanism: formation...

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Detalles Bibliográficos
Autores principales: Krachtus, Dieter, Smith, Jeremy C., Imhof, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321591/
https://www.ncbi.nlm.nih.gov/pubmed/30563005
http://dx.doi.org/10.3390/molecules23123342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321591/
https://www.ncbi.nlm.nih.gov/pubmed/30563005
http://dx.doi.org/10.3390/molecules23123342

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