Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box

Sox2 is a pioneer transcription factor that initiates cell fate reprogramming through locus-specific differential regulation. Mechanistically, it was assumed that Sox2 achieves its regulatory diversity via heterodimerization with partner transcription factors. Here, utilizing single-molecule fluores...

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Detalles Bibliográficos
Autores principales: Moosa, Mahdi Muhammad, Tsoi, Phoebe S., Choi, Kyoung-Jae, Ferreon, Allan Chris M., Ferreon, Josephine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321608/
https://www.ncbi.nlm.nih.gov/pubmed/30518054
http://dx.doi.org/10.3390/ijms19123865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321608/
https://www.ncbi.nlm.nih.gov/pubmed/30518054
http://dx.doi.org/10.3390/ijms19123865

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