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Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box

Sox2 is a pioneer transcription factor that initiates cell fate reprogramming through locus-specific differential regulation. Mechanistically, it was assumed that Sox2 achieves its regulatory diversity via heterodimerization with partner transcription factors. Here, utilizing single-molecule fluores...

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Detalles Bibliográficos
Autores principales:	Moosa, Mahdi Muhammad, Tsoi, Phoebe S., Choi, Kyoung-Jae, Ferreon, Allan Chris M., Ferreon, Josephine C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321608/ https://www.ncbi.nlm.nih.gov/pubmed/30518054 http://dx.doi.org/10.3390/ijms19123865

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