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Caspase-3 Mediated Cell Death in the Normal Development of the Mammalian Cerebellum

Caspase-3, onto which there is a convergence of the intrinsic and extrinsic apoptotic pathways, is the main executioner of apoptosis. We here review the current literature on the intervention of the protease in the execution of naturally occurring neuronal death (NOND) during cerebellar development....

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Detalles Bibliográficos
Autores principales: Lossi, Laura, Castagna, Claudia, Merighi, Adalberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321612/
https://www.ncbi.nlm.nih.gov/pubmed/30545052
http://dx.doi.org/10.3390/ijms19123999