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Impact of tRNA Modifications and tRNA-Modifying Enzymes on Proteostasis and Human Disease

Transfer RNAs (tRNAs) are key players of protein synthesis, as they decode the genetic information organized in mRNA codons, translating them into the code of 20 amino acids. To be fully active, tRNAs undergo extensive post-transcriptional modifications, catalyzed by different tRNA-modifying enzymes...

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Detalles Bibliográficos
Autores principales: Pereira, Marisa, Francisco, Stephany, Varanda, Ana Sofia, Santos, Mafalda, Santos, Manuel A. S., Soares, Ana Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321623/
https://www.ncbi.nlm.nih.gov/pubmed/30477220
http://dx.doi.org/10.3390/ijms19123738