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Impact of tRNA Modifications and tRNA-Modifying Enzymes on Proteostasis and Human Disease
Transfer RNAs (tRNAs) are key players of protein synthesis, as they decode the genetic information organized in mRNA codons, translating them into the code of 20 amino acids. To be fully active, tRNAs undergo extensive post-transcriptional modifications, catalyzed by different tRNA-modifying enzymes...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321623/ https://www.ncbi.nlm.nih.gov/pubmed/30477220 http://dx.doi.org/10.3390/ijms19123738 |