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Identification, Characterization and Quantification of Process-Related and Degradation Impurities in Lisdexamfetamine Dimesylate: Identifiction of Two New Compounds

Twelve impurities (process-related and degradation) in lisdexamfetamine dimesylate (LDX), a central nervous system (CNS) stimulant drug, were first separated and quantified by high-performance liquid chromatography (HPLC) and then identified by liquid chromatography mass spectrometry (LC-MS). The st...

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Detalles Bibliográficos
Autores principales: Gao, Shenghua, Meng, Lili, Zhao, Chunjie, Zhang, Tao, Qiu, Pengcheng, Zhang, Fuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321639/
https://www.ncbi.nlm.nih.gov/pubmed/30501039
http://dx.doi.org/10.3390/molecules23123125