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Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico

Tyrosinase is a key enzyme in melanin synthesis, catalyzing the initial rate-limiting steps of melanin synthesis. Abnormal and excessive melanin synthesis is the primary cause of serious skin disorders including melasma, senile lentigo, freckles, and age spots. In attempts to find potent and safe ty...

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Detalles Bibliográficos
Autores principales: Bang, EunJin, Noh, Sang-Gyun, Ha, Sugyeong, Jung, Hee Jin, Kim, Dae Hyun, Lee, A Kyoung, Hyun, Min Kyung, Kang, Dongwan, Lee, Sanggwon, Park, Chaeun, Moon, Hyung Ryong, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321646/
https://www.ncbi.nlm.nih.gov/pubmed/30551624
http://dx.doi.org/10.3390/molecules23123307