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Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico
Tyrosinase is a key enzyme in melanin synthesis, catalyzing the initial rate-limiting steps of melanin synthesis. Abnormal and excessive melanin synthesis is the primary cause of serious skin disorders including melasma, senile lentigo, freckles, and age spots. In attempts to find potent and safe ty...
Autores principales: | Bang, EunJin, Noh, Sang-Gyun, Ha, Sugyeong, Jung, Hee Jin, Kim, Dae Hyun, Lee, A Kyoung, Hyun, Min Kyung, Kang, Dongwan, Lee, Sanggwon, Park, Chaeun, Moon, Hyung Ryong, Chung, Hae Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321646/ https://www.ncbi.nlm.nih.gov/pubmed/30551624 http://dx.doi.org/10.3390/molecules23123307 |
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