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Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci

BACKGROUND: DNA methylation alteration extensively associates with smoking and is a plausible link between smoking and adverse health. We examined the association between epigenome-wide DNA methylation and serum cotinine levels as a proxy of nicotine exposure and smoking quantity, assessed the role...

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Detalles Bibliográficos
Autores principales: Gupta, Richa, van Dongen, Jenny, Fu, Yu, Abdellaoui, Abdel, Tyndale, Rachel F., Velagapudi, Vidya, Boomsma, Dorret I., Korhonen, Tellervo, Kaprio, Jaakko, Loukola, Anu, Ollikainen, Miina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321663/
https://www.ncbi.nlm.nih.gov/pubmed/30611298
http://dx.doi.org/10.1186/s13148-018-0606-9