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Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci
BACKGROUND: DNA methylation alteration extensively associates with smoking and is a plausible link between smoking and adverse health. We examined the association between epigenome-wide DNA methylation and serum cotinine levels as a proxy of nicotine exposure and smoking quantity, assessed the role...
Autores principales: | Gupta, Richa, van Dongen, Jenny, Fu, Yu, Abdellaoui, Abdel, Tyndale, Rachel F., Velagapudi, Vidya, Boomsma, Dorret I., Korhonen, Tellervo, Kaprio, Jaakko, Loukola, Anu, Ollikainen, Miina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321663/ https://www.ncbi.nlm.nih.gov/pubmed/30611298 http://dx.doi.org/10.1186/s13148-018-0606-9 |
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