Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species

BACKGROUND: Gambogic acid is a natural component isolated from gamboge that possesses anticancer properties. Our previous study suggested that gambogic acid might be involved in autophagy; however, its role in pancreatic cancer remained unclear. METHODS: Cell viability and apoptosis of pancreatic ca...

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Detalles Bibliográficos
Autores principales: Wang, Hongcheng, Zhao, Zhi, Lei, Shizhou, Li, Shaoli, Xiang, Zhen, Wang, Xiaoyu, Huang, Xiuyan, Xia, Guanggai, Huang, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321668/
https://www.ncbi.nlm.nih.gov/pubmed/30627053
http://dx.doi.org/10.1186/s12935-018-0705-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321668/
https://www.ncbi.nlm.nih.gov/pubmed/30627053
http://dx.doi.org/10.1186/s12935-018-0705-x

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