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Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

BACKGROUND: Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognise bacterial metabolites presented by MHC class I-related protein 1 (MR1). Bacterial dysbiosis has been implicated in auto-inflammatory disease development. We investigated MAIT cells in early, untreated rheu...

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Detalles Bibliográficos
Autores principales: Koppejan, Hester, Jansen, Diahann T. S. L., Hameetman, Marjolijn, Thomas, Ranjeny, Toes, Rene E. M., van Gaalen, Floris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321723/
https://www.ncbi.nlm.nih.gov/pubmed/30611306
http://dx.doi.org/10.1186/s13075-018-1799-1