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Low HIF-1α and low EGFR mRNA Expression Significantly Associate with Poor Survival in Soft Tissue Sarcoma Patients; the Proteins React Differently

In various tumors, the hypoxia inducible factor-1α (HIF-1α) and the epidermal growth factor-receptor (EGFR) have an impact on survival. Nevertheless, the prognostic impact of both markers for soft tissue sarcoma (STS) is not well studied. We examined 114 frozen tumor samples from adult soft tissue s...

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Detalles Bibliográficos
Autores principales: Rot, Swetlana, Taubert, Helge, Bache, Matthias, Greither, Thomas, Würl, Peter, Holzhausen, Hans-Jürgen, Eckert, Alexander W., Vordermark, Dirk, Kappler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321736/
https://www.ncbi.nlm.nih.gov/pubmed/30513863
http://dx.doi.org/10.3390/ijms19123842