Rapid generation of gene-targeted EPS-derived mouse models through tetraploid complementation

One major strategy to generate genetically modified mouse models is gene targeting in mouse embryonic stem (ES) cells, which is used to produce gene-targeted mice for wide applications in biomedicine. However, a major bottleneck in this approach is that the robustness of germline transmission of gen...

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Detalles Bibliográficos
Autores principales: Li, Haibo, Zhao, Chaoran, Xu, Jun, Xu, Yaxing, Cheng, Chunmei, Liu, Yinan, Wang, Ting, Du, Yaqin, Xie, Liangfu, Zhao, Jingru, Han, Yanchuang, Wang, Xiaobao, Bai, Yun, Deng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2018
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321812/
https://www.ncbi.nlm.nih.gov/pubmed/29948855
http://dx.doi.org/10.1007/s13238-018-0556-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321812/
https://www.ncbi.nlm.nih.gov/pubmed/29948855
http://dx.doi.org/10.1007/s13238-018-0556-1

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