Human Norovirus Epitope D Plasticity Allows Escape from Antibody Immunity without Loss of Capacity for Binding Cellular Ligands

Emergent strains of human norovirus seed pandemic waves of disease. These new strains have altered ligand binding and antigenicity characteristics. Study of viral variants isolated from immunosuppressed patients with long-term norovirus infection indicates that initial virus in vivo evolution occurs...

Descripción completa

Detalles Bibliográficos
Autores principales: Lindesmith, Lisa C., Brewer-Jensen, Paul D., Mallory, Michael L., Yount, Boyd, Collins, Matthew H., Debbink, Kari, Graham, Rachel L., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321922/
https://www.ncbi.nlm.nih.gov/pubmed/30355694
http://dx.doi.org/10.1128/JVI.01813-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321922/
https://www.ncbi.nlm.nih.gov/pubmed/30355694
http://dx.doi.org/10.1128/JVI.01813-18

Ejemplares similares