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Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD

Duchenne muscular dystrophy (DMD) is a lethal, X-linked muscle-wasting disease caused by lack of the cytoskeletal protein dystrophin. Constitutive utrophin expression, a structural and functional paralogue of dystrophin, can successfully prevent the dystrophic pathology in the dystrophin-deficient m...

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Detalles Bibliográficos
Autores principales: Guiraud, Simon, Edwards, Benjamin, Squire, Sarah E, Moir, Lee, Berg, Adam, Babbs, Arran, Ramadan, Nesrine, Wood, Matthew J, Davies, Kay E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322073/
https://www.ncbi.nlm.nih.gov/pubmed/30304405
http://dx.doi.org/10.1093/hmg/ddy353