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Epigenetic and Transcriptome Profiling Identifies a Population of Visceral Adipose-Derived Progenitor Cells with the Potential to Differentiate into an Endocrine Pancreatic Lineage

Type 1 diabetes (T1D) is characterized by the loss of insulin-producing β-cells in the pancreas. T1D can be treated using cadaveric islet transplantation, but this therapy is severely limited by a lack of pancreas donors. To develop an alternative cell source for transplantation therapy, we carried...

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Detalles Bibliográficos
Autores principales: Williams, Michael D., Joglekar, Mugdha V., Satoor, Sarang N., Wong, Wilson, Keramidaris, Effie, Rixon, Amanda, O’Connell, Philip, Hawthorne, Wayne J., Mitchell, Geraldine M., Hardikar, Anandwardhan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322142/
https://www.ncbi.nlm.nih.gov/pubmed/30376726
http://dx.doi.org/10.1177/0963689718808472