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Epigenetic and Transcriptome Profiling Identifies a Population of Visceral Adipose-Derived Progenitor Cells with the Potential to Differentiate into an Endocrine Pancreatic Lineage
Type 1 diabetes (T1D) is characterized by the loss of insulin-producing β-cells in the pancreas. T1D can be treated using cadaveric islet transplantation, but this therapy is severely limited by a lack of pancreas donors. To develop an alternative cell source for transplantation therapy, we carried...
Autores principales: | Williams, Michael D., Joglekar, Mugdha V., Satoor, Sarang N., Wong, Wilson, Keramidaris, Effie, Rixon, Amanda, O’Connell, Philip, Hawthorne, Wayne J., Mitchell, Geraldine M., Hardikar, Anandwardhan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322142/ https://www.ncbi.nlm.nih.gov/pubmed/30376726 http://dx.doi.org/10.1177/0963689718808472 |
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