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Defining Pharmacological Targets by Analysis of Virus–Host Protein Interactions

Viruses are obligate parasites that depend on cellular factors for replication. Pharmacological inhibition of essential viral proteins, mostly enzymes, is an effective therapeutic alternative in the absence of effective vaccines. However, this strategy commonly encounters drug resistance mechanisms...

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Detalles Bibliográficos
Autores principales: Llano, Manuel, Peña-Hernandez, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322211/
https://www.ncbi.nlm.nih.gov/pubmed/29459033
http://dx.doi.org/10.1016/bs.apcsb.2017.11.001