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The circadian regulator Bmal1 in joint mesenchymal cells regulates both joint development and inflammatory arthritis

BACKGROUND: The circadian clock plays a crucial role in regulating physiology and is important for maintaining immune homeostasis and responses to inflammatory stimuli. Inflammatory arthritis often shows diurnal variation in disease symptoms and disease markers, and it is now established that cellul...

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Detalles Bibliográficos
Autores principales: Hand, Laura E., Dickson, Suzanna H., Freemont, Anthony J., Ray, David W., Gibbs, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322248/
https://www.ncbi.nlm.nih.gov/pubmed/30612576
http://dx.doi.org/10.1186/s13075-018-1770-1