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Global distribution of DNA hydroxymethylation and DNA methylation in chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) has been a good model system to understand the functional role of 5-methylcytosine (5-mC) in cancer progression. More recently, an oxidized form of 5-mC, 5-hydroxymethylcytosine (5-hmC) has gained lot of attention as a regulatory epigenetic modification...

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Detalles Bibliográficos
Autores principales: Wernig-Zorc, Sara, Yadav, Mukesh Pratap, Kopparapu, Pradeep Kumar, Bemark, Mats, Kristjansdottir, Hallgerdur Lind, Andersson, Per-Ola, Kanduri, Chandrasekhar, Kanduri, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322269/
https://www.ncbi.nlm.nih.gov/pubmed/30616658
http://dx.doi.org/10.1186/s13072-018-0252-7