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Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria

BACKGROUND: The ability of MDR Gram-negative bacteria to evade even antibiotics of last resort is a severe global challenge. The development pipeline for conventional antibiotics cannot address this issue, but antimicrobial peptides (AMPs) offer an alternative solution. OBJECTIVES: Two insect-derive...

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Detalles Bibliográficos
Autores principales: Hirsch, Rolf, Wiesner, Jochen, Marker, Alexander, Pfeifer, Yvonne, Bauer, Armin, Hammann, Peter E, Vilcinskas, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322280/
https://www.ncbi.nlm.nih.gov/pubmed/30272195
http://dx.doi.org/10.1093/jac/dky386