Lobar evenness of deposition/retention in rat lungs of inhaled silver nanoparticles: an approach for reducing animal use while maximizing endpoints

BACKGROUND: Information on particle deposition, retention and clearance are important for the evaluation of the risk of inhaled nanomaterials to human health. Recent revised OECD inhalation toxicity test guidelines require to evaluate the lung burden of nanomaterials after rodent subacute and subchr...

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Detalles Bibliográficos
Autores principales: Park, Jung Duck, Kim, Jin Kwon, Jo, Mi Seong, Kim, Young Hun, Jeon, Ki Soo, Lee, Ji Hyun, Faustman, Elaine M., Lee, Hong Ku, Ahn, Kangho, Gulumian, Mary, Oberdörster, Günter, Yu, Il Je
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322301/
https://www.ncbi.nlm.nih.gov/pubmed/30616672
http://dx.doi.org/10.1186/s12989-018-0286-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322301/
https://www.ncbi.nlm.nih.gov/pubmed/30616672
http://dx.doi.org/10.1186/s12989-018-0286-9

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