Cargando…

KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis

BACKGROUND: Fibroblast-like synoviocytes (FLS) and CCR7(−) effector memory T (T(EM)) cells are two of the major cell types implicated in the progression of rheumatoid arthritis (RA). In particular, FLS become highly invasive, whereas T(EM) cells proliferate and secrete proinflammatory cytokines, dur...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanner, Mark R., Pennington, Michael W., Chauhan, Satendra S., Laragione, Teresina, Gulko, Pércio S., Beeton, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322314/
https://www.ncbi.nlm.nih.gov/pubmed/30612588
http://dx.doi.org/10.1186/s13075-018-1783-9