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KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis
BACKGROUND: Fibroblast-like synoviocytes (FLS) and CCR7(−) effector memory T (T(EM)) cells are two of the major cell types implicated in the progression of rheumatoid arthritis (RA). In particular, FLS become highly invasive, whereas T(EM) cells proliferate and secrete proinflammatory cytokines, dur...
Autores principales: | Tanner, Mark R., Pennington, Michael W., Chauhan, Satendra S., Laragione, Teresina, Gulko, Pércio S., Beeton, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322314/ https://www.ncbi.nlm.nih.gov/pubmed/30612588 http://dx.doi.org/10.1186/s13075-018-1783-9 |
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