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Simultaneous Quantification of Plasmodium Antigens and Host Factor C-Reactive Protein in Asymptomatic Individuals with Confirmed Malaria by Use of a Novel Multiplex Immunoassay

Malaria rapid diagnostic tests (RDTs) primarily detect Plasmodium falciparum antigen histidine-rich protein 2 (HRP2) and the malaria-conserved antigen lactate dehydrogenase (LDH) for P. vivax and other malaria species. The performance of RDTs and their utility is dependent on circulating antigen con...

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Detalles Bibliográficos
Autores principales: Jang, Ihn Kyung, Tyler, Abby, Lyman, Chris, Kahn, Maria, Kalnoky, Michael, Rek, John C., Arinaitwe, Emmanuel, Adrama, Harriet, Murphy, Maxwell, Imwong, Mallika, Ling, Clare L., Proux, Stephane, Haohankhunnatham, Warat, Rist, Melissa, Seilie, Annette M., Hanron, Amelia, Daza, Glenda, Chang, Ming, Das, Smita, Barney, Rebecca, Rashid, Andrew, Landier, Jordi, Boyle, David S., Murphy, Sean C., McCarthy, James S., Nosten, François, Greenhouse, Bryan, Domingo, Gonzalo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322473/
https://www.ncbi.nlm.nih.gov/pubmed/30404944
http://dx.doi.org/10.1128/JCM.00948-18