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Identification of key genes and specific pathways potentially involved in androgen-independent, mitoxantrone-resistant prostate cancer
BACKGROUND: Resistance to mitoxantrone (MTX), an anthracenedione antineoplastic agent used in advanced and metastatic androgen-refractory prostate cancer (PCa), seriously limits therapeutic success. METHODS: Xenografts from two human PCa cell lines (VCaP and CWR22) were established in male severe co...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322516/ https://www.ncbi.nlm.nih.gov/pubmed/30655694 http://dx.doi.org/10.2147/CMAR.S179467 |