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Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension

PURPOSE: Reoxygenation after hypoxia can increase reactive oxygen species and upregulate autophagy. We determined, for the first time, the impact of elevated IOP on hypoxia induction, superoxide accumulation, and autophagy in a bead model of glaucoma. METHOD: Ocular hypertension was achieved with ma...

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Detalles Bibliográficos
Autores principales: Jassim, Assraa H., Inman, Denise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322635/
https://www.ncbi.nlm.nih.gov/pubmed/30601926
http://dx.doi.org/10.1167/iovs.18-24977