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rs187960998 polymorphism in miR-211 prevents development of human colon cancer by deregulation of 3′UTR in CHD5

BACKGROUND: Previous research indicated that overexpression of miRNA-211 could promote colorectal cancer cell growth by targeting tumor suppressive gene Chromodomain-helicase-DNA-binding protein 5 (CHD5) in human colon cancer (CC). Moreover, the function of the single-nucleotide polymorphism (SNP) l...

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Detalles Bibliográficos
Autores principales: Zhu, Limei, Wang, Ran, Zhang, Li, Zuo, Chunlei, Zhang, Rui, Zhao, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322703/
https://www.ncbi.nlm.nih.gov/pubmed/30655677
http://dx.doi.org/10.2147/OTT.S180935