Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

To understand drug combination effect, it is necessary to decipher the interactions between drug targets—many of which are signaling molecules. Previously, such signaling pathway models are largely based on the compilation of literature data from heterogeneous cellular contexts. Indeed, de novo reco...

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Detalles Bibliográficos
Autores principales: Bansal, Mukesh, He, Jing, Peyton, Michael, Kustagi, Manjunath, Iyer, Archana, Comb, Michael, White, Michael, Minna, John D., Califano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322741/
https://www.ncbi.nlm.nih.gov/pubmed/30615629
http://dx.doi.org/10.1371/journal.pone.0208646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322741/
https://www.ncbi.nlm.nih.gov/pubmed/30615629
http://dx.doi.org/10.1371/journal.pone.0208646

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