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Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis
To understand drug combination effect, it is necessary to decipher the interactions between drug targets—many of which are signaling molecules. Previously, such signaling pathway models are largely based on the compilation of literature data from heterogeneous cellular contexts. Indeed, de novo reco...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322741/ https://www.ncbi.nlm.nih.gov/pubmed/30615629 http://dx.doi.org/10.1371/journal.pone.0208646 |