Cargando…

Spatial control of neuronal metabolism through glucose-mediated mitochondrial transport regulation

Eukaryotic cells modulate their metabolism by organizing metabolic components in response to varying nutrient availability and energy demands. In rat axons, mitochondria respond to glucose levels by halting active transport in high glucose regions. We employ quantitative modeling to explore physical...

Descripción completa

Detalles Bibliográficos
Autores principales: Agrawal, Anamika, Pekkurnaz, Gulcin, Koslover, Elena F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322862/
https://www.ncbi.nlm.nih.gov/pubmed/30561333
http://dx.doi.org/10.7554/eLife.40986