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Targeting JNK pathway promotes human hematopoietic stem cell expansion

The limited number of human hematopoietic stem cells (HSCs) has restrained their widespread clinical application. Despite great efforts in recent years, the in vitro expansion of HSCs remains a challenge due to incomplete understanding of the signaling networks underlying HSC self-renewal. Here, we...

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Detalles Bibliográficos
Autores principales: Xiao, Xiong, Lai, Weifeng, Xie, Huangfan, Liu, Yang, Guo, Weijie, Liu, Yifang, Li, Yu, Li, Yuanjun, Zhang, Jingliang, Chen, Wenhan, Shi, Minhui, Shang, Lijun, Yin, Ming, Wang, Chengyan, Deng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323118/
https://www.ncbi.nlm.nih.gov/pubmed/30622738
http://dx.doi.org/10.1038/s41421-018-0072-8