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Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait

Survival to extreme ages clusters within families. However, identifying genetic loci conferring longevity and low morbidity in such longevous families is challenging. There is debate concerning the survival percentile that best isolates the genetic component in longevity. Here, we use three-generati...

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Detalles Bibliográficos
Autores principales: van den Berg, Niels, Rodríguez-Girondo, Mar, van Dijk, Ingrid K., Mourits, Rick J., Mandemakers, Kees, Janssens, Angelique A. P. O., Beekman, Marian, Smith, Ken R., Slagboom, P. Eline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323124/
https://www.ncbi.nlm.nih.gov/pubmed/30617297
http://dx.doi.org/10.1038/s41467-018-07925-0