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NOTUM inhibition increases endocortical bone formation and bone strength

The disability, mortality and costs caused by non-vertebral osteoporotic fractures are enormous. Existing osteoporosis therapies are highly effective at reducing vertebral but not non-vertebral fractures. Cortical bone is a major determinant of non-vertebral bone strength. To identify novel osteopor...

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Detalles Bibliográficos
Autores principales: Brommage, Robert, Liu, Jeff, Vogel, Peter, Mseeh, Faika, Thompson, Andrea Y., Potter, David G., Shadoan, Melanie K., Hansen, Gwenn M., Jeter-Jones, Sabrina, Cui, Jie, Bright, Dawn, Bardenhagen, Jennifer P., Doree, Deon D., Movérare-Skrtic, Sofia, Nilsson, Karin H., Henning, Petra, Lerner, Ulf H., Ohlsson, Claes, Sands, Arthur T., Tarver, James E., Powell, David R., Zambrowicz, Brian, Liu, Qingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323125/
https://www.ncbi.nlm.nih.gov/pubmed/30622831
http://dx.doi.org/10.1038/s41413-018-0038-3