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Ginsenoside Rk1 ameliorates paracetamol-induced hepatotoxicity in mice through inhibition of inflammation, oxidative stress, nitrative stress and apoptosis

BACKGROUND: Frequent overdose of paracetamol (APAP) has become the major cause of acute liver injury. The present study was designed to evaluate the potential protective effects of ginsenoside Rk1 on APAP-induced hepatotoxicity and investigate the underlying mechanisms for the first time. METHODS: M...

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Detalles Bibliográficos
Autores principales: Hu, Jun-Nan, Xu, Xing-Yue, Li, Wei, Wang, Yi-Ming, Liu, Ying, Wang, Zi, Wang, Ying-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323149/
https://www.ncbi.nlm.nih.gov/pubmed/30662289
http://dx.doi.org/10.1016/j.jgr.2017.07.003