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Ginsenoside Rk1 ameliorates paracetamol-induced hepatotoxicity in mice through inhibition of inflammation, oxidative stress, nitrative stress and apoptosis
BACKGROUND: Frequent overdose of paracetamol (APAP) has become the major cause of acute liver injury. The present study was designed to evaluate the potential protective effects of ginsenoside Rk1 on APAP-induced hepatotoxicity and investigate the underlying mechanisms for the first time. METHODS: M...
Autores principales: | Hu, Jun-Nan, Xu, Xing-Yue, Li, Wei, Wang, Yi-Ming, Liu, Ying, Wang, Zi, Wang, Ying-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323149/ https://www.ncbi.nlm.nih.gov/pubmed/30662289 http://dx.doi.org/10.1016/j.jgr.2017.07.003 |
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