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Colon targeted beads loaded with pterostilbene: Formulation, optimization, characterization and in vivo evaluation

BACKGROUND: Pterostilbene has a proven chemopreventive effect for colon carcinogenesis but suffers low bioavailability limitations and therefore unable to reach the colonic tissue. OBJECTIVE AND METHODOLOGY: To overcome the issue of low bioavailability, pterostilbene was formulated into an oral colo...

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Detalles Bibliográficos
Autores principales: Ansari, Mudassir, Sadarani, Bhakti, Majumdar, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323150/
https://www.ncbi.nlm.nih.gov/pubmed/30662309
http://dx.doi.org/10.1016/j.jsps.2018.07.021