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Colon targeted beads loaded with pterostilbene: Formulation, optimization, characterization and in vivo evaluation
BACKGROUND: Pterostilbene has a proven chemopreventive effect for colon carcinogenesis but suffers low bioavailability limitations and therefore unable to reach the colonic tissue. OBJECTIVE AND METHODOLOGY: To overcome the issue of low bioavailability, pterostilbene was formulated into an oral colo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323150/ https://www.ncbi.nlm.nih.gov/pubmed/30662309 http://dx.doi.org/10.1016/j.jsps.2018.07.021 |