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New insights into the mechanism of antifungal action of 8-hydroxyquinolines

The 8-hydroxyquinoline core is a privileged scaffold for drug design explored to afford novel derivatives endowed with biological activity. Our research aimed at clarifying the antifungal mechanism of action of clioquinol, 8-hydroxy-5-quinolinesulfonic acid, and 8-hydroxy-7-iodo-5-quinolinesulfonic...

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Detalles Bibliográficos
Autores principales: Pippi, Bruna, Lopes, William, Reginatto, Paula, Silva, Fernanda Émili Klein, Joaquim, Angélica Rocha, Alves, Ricardo José, Silveira, Gustavo Pozza, Vainstein, Marilene Henning, Andrade, Saulo Fernandes, Fuentefria, Alexandre Meneghello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323154/
https://www.ncbi.nlm.nih.gov/pubmed/30662305
http://dx.doi.org/10.1016/j.jsps.2018.07.017