Cargando…

Melatonin ameliorates ANIT-induced cholestasis by activating Nrf2 through a PI3K/Akt-dependent pathway in rats

Cholestasis is a devastating liver condition which is increasing in prevalence worldwide; however, its underlying pathogenic mechanisms remain to be fully elucidated. It was hypothesised that melatonin may alleviate the hepatic injury associated with cholestasis due to its established antioxidant ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yunzhou, Yu, Han, Xu, Zongying, Shi, Shaohua, Wang, Dingnan, Shi, Xinghua, Wang, Yuchen, Zeng, Baihui, Deng, Huifang, Deng, Xiulan, Zhong, Xianggen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323259/
https://www.ncbi.nlm.nih.gov/pubmed/30569102
http://dx.doi.org/10.3892/mmr.2018.9746