Cargando…
Melatonin ameliorates ANIT-induced cholestasis by activating Nrf2 through a PI3K/Akt-dependent pathway in rats
Cholestasis is a devastating liver condition which is increasing in prevalence worldwide; however, its underlying pathogenic mechanisms remain to be fully elucidated. It was hypothesised that melatonin may alleviate the hepatic injury associated with cholestasis due to its established antioxidant ef...
Autores principales: | Li, Yunzhou, Yu, Han, Xu, Zongying, Shi, Shaohua, Wang, Dingnan, Shi, Xinghua, Wang, Yuchen, Zeng, Baihui, Deng, Huifang, Deng, Xiulan, Zhong, Xianggen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323259/ https://www.ncbi.nlm.nih.gov/pubmed/30569102 http://dx.doi.org/10.3892/mmr.2018.9746 |
Ejemplares similares
-
iTRAQ-based quantitative proteomics analysis of the hepatoprotective effect of melatonin on ANIT-induced cholestasis in rats
por: Wang, Dingnan, et al.
Publicado: (2021) -
Identification of potential biomarkers in cholestasis and the therapeutic effect of melatonin by metabolomics, multivariate data and pathway analyses
por: Yu, Han, et al.
Publicado: (2018) -
Paeonia lactiflora Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway
por: Ma, Xiao, et al.
Publicado: (2015) -
SRT1720 Alleviates ANIT-Induced Cholestasis in a Mouse Model
por: Yu, Linxi, et al.
Publicado: (2017) -
Mechanism of crocin I on ANIT-induced intrahepatic cholestasis by combined metabolomics and transcriptomics
por: Song, Dandan, et al.
Publicado: (2023)