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Novel adeno-associated virus-based genetic vaccines encoding hepatitis C virus E2 glycoprotein elicit humoral immune responses in mice

Hepatitis C virus (HCV) infection remains a major public health issue despite the introduction of several direct-acting antiviral agents (DAAs), with some 185 million individuals infected with HCV worldwide. There is an urgent need for an effective prophylactic HCV vaccine. In the present study, we...

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Detalles Bibliográficos
Autores principales: Zhu, Fengqin, Wang, Yibo, Xu, Zhen, Qu, Haiyang, Zhang, Hairong, Niu, Lingling, Xue, Honglu, Jing, Dehuai, He, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323296/
https://www.ncbi.nlm.nih.gov/pubmed/30569131
http://dx.doi.org/10.3892/mmr.2018.9739