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In Vivo Resistance to Ceftolozane/Tazobactam in Pseudomonas aeruginosa Arising by AmpC- and Non-AmpC-Mediated Pathways

Two pairs of ceftolozane/tazobactam susceptible/resistant P. aeruginosa were isolated from 2 patients after exposure to β-lactams. The genetic basis of ceftolozane/tazobactam resistance was evaluated, and β-lactam-resistant mechanisms were assessed by phenotypic assays. Whole genome sequencing ident...

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Detalles Bibliográficos
Autores principales: Skoglund, Erik, Abodakpi, Henrietta, Rios, Rafael, Diaz, Lorena, De La Cadena, Elsa, Dinh, An Q., Ardila, Javier, Miller, William R., Munita, Jose M., Arias, Cesar A., Tam, Vincent H., Tran, Truc T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323425/
https://www.ncbi.nlm.nih.gov/pubmed/30675406
http://dx.doi.org/10.1155/2018/9095203