Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice

Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme for metabolism of reactive aldehydes, but its role during liver ischemia-reperfusion injury (IRI) remains unclear. In the present study, we investigated the effects of the ALDH2 activator, Alda-1, in liver IRI and elucidated the underlying mechanisms....

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Detalles Bibliográficos
Autores principales: Li, Meng, Xu, Min, Li, Jichang, Chen, Lili, Xu, Dongwei, Tong, Ying, Zhang, Jianjun, Wu, Hailong, Kong, Xiaoni, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323494/
https://www.ncbi.nlm.nih.gov/pubmed/30671488
http://dx.doi.org/10.1155/2018/9807139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323494/
https://www.ncbi.nlm.nih.gov/pubmed/30671488
http://dx.doi.org/10.1155/2018/9807139

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