Cargando…
Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice
Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme for metabolism of reactive aldehydes, but its role during liver ischemia-reperfusion injury (IRI) remains unclear. In the present study, we investigated the effects of the ALDH2 activator, Alda-1, in liver IRI and elucidated the underlying mechanisms....
Autores principales: | Li, Meng, Xu, Min, Li, Jichang, Chen, Lili, Xu, Dongwei, Tong, Ying, Zhang, Jianjun, Wu, Hailong, Kong, Xiaoni, Xia, Qiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323494/ https://www.ncbi.nlm.nih.gov/pubmed/30671488 http://dx.doi.org/10.1155/2018/9807139 |
Ejemplares similares
-
The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy
por: Xu, Dongwei, et al.
Publicado: (2017) -
Effects of Alda-1, an Aldehyde Dehydrogenase-2 Agonist, on Hypoglycemic Neuronal Death
por: Ikeda, Tetsuhiko, et al.
Publicado: (2015) -
Characterization of the East Asian Variant of Aldehyde Dehydrogenase-2: BIOACTIVATION OF NITROGLYCERIN AND EFFECTS OF Alda-1
por: Beretta, Matteo, et al.
Publicado: (2010) -
The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus
por: Imber, Marcel, et al.
Publicado: (2018) -
DJ-1 Deficiency in Hepatocytes Improves Liver Ischemia-Reperfusion Injury by Enhancing Mitophagy
por: Xu, Min, et al.
Publicado: (2021)