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Estradiol Alleviates Intervertebral Disc Degeneration through Modulating the Antioxidant Enzymes and Inhibiting Autophagy in the Model of Menopause Rats

OBJECTIVE: To investigate the effects of menopause on redox balance in the intervertebral disc and to examine whether oxidative stress and autophagy were associated with disc degeneration in menopause rats. METHODS: Thirty female Sprague-Dawley rats were randomly divided into three groups (sham, ova...

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Detalles Bibliográficos
Autores principales: Jin, Lin-Yu, Lv, Zhen-Dong, Wang, Kun, Qian, Lie, Song, Xiao-Xing, Li, Xin-Feng, Shen, Hong-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323532/
https://www.ncbi.nlm.nih.gov/pubmed/30671175
http://dx.doi.org/10.1155/2018/7890291