Cargando…

Estradiol Alleviates Intervertebral Disc Degeneration through Modulating the Antioxidant Enzymes and Inhibiting Autophagy in the Model of Menopause Rats

OBJECTIVE: To investigate the effects of menopause on redox balance in the intervertebral disc and to examine whether oxidative stress and autophagy were associated with disc degeneration in menopause rats. METHODS: Thirty female Sprague-Dawley rats were randomly divided into three groups (sham, ova...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Lin-Yu, Lv, Zhen-Dong, Wang, Kun, Qian, Lie, Song, Xiao-Xing, Li, Xin-Feng, Shen, Hong-Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323532/ https://www.ncbi.nlm.nih.gov/pubmed/30671175 http://dx.doi.org/10.1155/2018/7890291

Ejemplares similares

Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy
por: Zhang, Shuwen, et al.
Publicado: (2021)

Danshen Attenuates Intervertebral Disc Degeneration via Antioxidation in SD Rats
por: Qin, Rongqing, et al.
Publicado: (2020)

Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells
por: Xie, Chenglong, et al.
Publicado: (2022)

The circadian rhythm in intervertebral disc degeneration: an autophagy connection
por: Zhang, Tai-Wei, et al.
Publicado: (2020)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

Senolytics: Eliminating Senescent Cells and Alleviating Intervertebral Disc Degeneration
por: Wu, Yuhao, et al.
Publicado: (2022)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

Pulsed Electromagnetic Field Alleviates Intervertebral Disc Degeneration by Activating Sirt1-Autophagy Signaling Network
por: Zheng, Yi, et al.
Publicado: (2022)

Bmi deficiency causes oxidative stress and intervertebral disc degeneration which can be alleviated by antioxidant treatment
por: Zhang, Qunhu, et al.
Publicado: (2020)

Innovative immune mechanisms and antioxidative therapies of intervertebral disc degeneration
por: Wei, Bingqian, et al.
Publicado: (2022)

Antioxidative behavior of a2-macroglobulin in intervertebral disc degeneration
por: Chen, Yuhong, et al.
Publicado: (2023)

BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells
por: Xiao, Quan, et al.
Publicado: (2022)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Macrophages and Intervertebral Disc Degeneration
por: Koroth, Jinsha, et al.
Publicado: (2023)

Autophagy and mTOR signaling during intervertebral disc aging and degeneration
por: Yurube, Takashi, et al.
Publicado: (2020)

Yiqi Huoxue Recipe Delayed Intervertebral Disc Degeneration by Activating Autophagy
por: Dai, Feng, et al.
Publicado: (2021)

Targeting Autophagy for Developing New Therapeutic Strategy in Intervertebral Disc Degeneration
por: Bahar, Md Entaz, et al.
Publicado: (2022)

The Nrf2 antioxidant defense system in intervertebral disc degeneration: Molecular insights
por: Xiang, Qian, et al.
Publicado: (2022)

How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration
por: Zhang, Qing-Xiang, et al.
Publicado: (2023)

Identification of key genes and potential mechanisms based on the autophagy regulatory network in intervertebral disc degeneration
por: Lv, Chang, et al.
Publicado: (2022)

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Diabetes and intervertebral disc degeneration: A Mendelian randomization study
por: Jin, Peihao, et al.
Publicado: (2023)

Diagnostic model based on key autophagy-related genes in intervertebral disc degeneration
por: Wang, Yifeng, et al.
Publicado: (2023)

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration
por: Munir, Sabrina, et al.
Publicado: (2018)

Angiogenesis in the degeneration of the lumbar intervertebral disc
por: David, Gh, et al.
Publicado: (2010)

Intervertebral disc degeneration therapies in human
por: Richardson, Stephen M
Publicado: (2015)

Genetic factors in intervertebral disc degeneration
por: Feng, Yi, et al.
Publicado: (2016)

The Role of Adipokines in Intervertebral Disc Degeneration
por: Sharma, Anirudh
Publicado: (2018)

Molecular Mechanisms of Intervertebral Disc Degeneration
por: Rider, Sean M., et al.
Publicado: (2018)

Genetic Therapy for Intervertebral Disc Degeneration
por: Roh, Eun Ji, et al.
Publicado: (2021)

Cervical intervertebral disc degeneration and dizziness
por: Liu, Tang-Hua, et al.
Publicado: (2021)

The Proteolysis of ECM in Intervertebral Disc Degeneration
por: Liang, Huaizhen, et al.
Publicado: (2022)

The role of ferroptosis in intervertebral disc degeneration
por: Fan, Chunyang, et al.
Publicado: (2023)

Role of Necroptosis in Intervertebral Disc Degeneration
por: Khaleque, Md Abdul, et al.
Publicado: (2023)

Editorial: Cell-based therapeutics for intervertebral disc degeneration
por: Li, Zhen, et al.
Publicado: (2023)

Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction
por: Dai, Zhanqiu, et al.
Publicado: (2022)

Quercetin Suppresses Apoptosis and Attenuates Intervertebral Disc Degeneration via the SIRT1-Autophagy Pathway
por: Wang, Dong, et al.
Publicado: (2020)

Emerging roles of RNA binding proteins in intervertebral disc degeneration and osteoarthritis
por: Li, Wen, et al.
Publicado: (2023)

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
por: Millward-Sadler, S Jane, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_o3f9ljigg8msmp25h4vn2rreah